Invigorating IVIG

InvIGOrating mRNAs during Quiescence.

In this issue of Molecular Cell, De Virgilio and colleagues (Talarek et al., 2010) identify the Igo1/2 proteins as factors that protect mRNAs from degradation during quiescence.

IVIg conducts DC-platelet nuptials.

and -thromboglobulin) supports a packing or sorting defect rather than a defect in protein synthesis.5,7 By analogy, mice lacking chondroitin sulfate have -granules deficient in PF4, -thromboglobulin, and platelet-derived growth factor because of a granule-packing defect9 and patients lacking the vesicle-sorting protein VPS33B have -granule deficiency.10 Defects in protein packing, vesicle traf...

Treatment of scleromyxedema with IVIg

Results An 18 year old male presented with a rash of three weeks duration. Soon after the rash appeared, he developed pain and swelling of the right hand, as well as numbness and tingling of the right forearm. A recreational weight lifter, he noticed progressively decreasing stamina and amount of weight that he could lift. Swelling of the eyelids and bridge of nose prompted treatment for an all...

Resistance to intravenous immunoglobulin (IVIG) in Kawasaki disease: no influence of different IVIG lot utilisation.

Intravenous immunoglobulin (IVIG) therapy for immunologic abortion

Recurrent pregnancy loss associated with immunologic abnormalities has been termed immunologic abortion. Immunologic abortion occurs primarily in women over the age of 30 years and may affect either natural or in-vitro fertilization (IVF)-induced pregnancy. In this article, we review the humoral and cellular immunologic abnormalities that have been associated with this form of recurrent abortio...